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DNA methylation
Blood DNA Methylation Age (GSE40279)
DNA methylation measurements from human whole blood, collected with Illumina HumanMethylation450 arrays across people of different ages. The regression task is to predict a participant's chronological age from methylation levels at CpG sites.
RegressionLicence: NCBI GEO public data; study-specific terms require verification before re-hostingGEO-GSE40279-Methylation-AgeTarget: age (y)geo_matrix ↗
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At this operating point
Model comparison
p=10,000, n=100 · Lower RMSE is better
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Random Forest is marked with a diamond. Models are ordered by the selected metric.
Across sample budgets
Learning curves
All metric values at this operating point
| Model | RMSE | MAE | R² |
|---|---|---|---|
| RealTabPFN 2.5 | 10.63 | 8.894 | 0.138 |
| TabFM | 10.93 | 9.055 | 0.08505 |
| RealTabPFN v2 | 11.4 | 9.5 | 0.03343 |
| Kumo Tabular (M) | 11.54 | 9.692 | 0.007528 |
| TabPFN 3.5 | 11.55 | 9.704 | -0.03883 |
| LimiX2 | 11.69 | 9.45 | -0.05634 |
| Causilo | 12.16 | 10.27 | -0.1284 |
| MITRA | 12.23 | 10.2 | -0.1471 |
| XGBoost (tuned) | 12.43 | 10.05 | -0.2375 |
| GeneICL | 12.47 | 10.59 | -0.1855 |
| Logistic Regression | 12.85 | 10.79 | -0.2205 |
| Random Forest | 12.86 | 10.53 | -0.2853 |
| Logistic Regression (tuned) | 13.07 | 10.89 | -0.2619 |
| Random Forest (tuned) | 13.65 | 11.27 | -0.4033 |
| Extra Trees (tuned) | 13.66 | 11.27 | -0.3885 |
| Extra Trees | 13.68 | 11.27 | -0.44 |
| TabM | 13.77 | 11.42 | -0.3854 |
| XGBoost | 14.32 | 11.79 | -0.6065 |
| TabDPT | 14.47 | 12.03 | -0.6149 |
| AutoGluon | 14.48 | 12.01 | -0.6045 |
| MLP (tuned) | 14.59 | 12.26 | -0.6562 |
| MLP | 14.88 | 12.69 | -0.6098 |
| RealMLP | 14.96 | 12.49 | -0.778 |